I never mess with grid, but here is a way that I would do it. Make everything in a hash, so you can easily retreive values, by specifying page, and frame. (I may have made some logic errors in the frame setup...and the boxes can be aligned with padding your text with spaces). I'm in a hurry....so test,test,test, but it appears to work.

#!/usr/bin/perl 
use warnings;
use strict;
use Tk;
use Tk::NoteBook;
require Tk::Pane;
use Tk::LabEntry;

my $mw = MainWindow->new();
$mw->geometry( "600x500" );
my $book = $mw->NoteBook()->pack( -fill=>'both', -expand=>1 );

my %hash;

my @tabs = (1..5);

foreach my $tab(@tabs){
$hash{$tab}{'frame'} = $book->add( "Sheet $tab", -label=>"program $tab
+");
#$hash{$tab}{'frame'} = $book->add( "Sheet $tab", -label=>"program $ta
+b");
}


 #make a Scolled Pane in every tab, with 2 frames for columns
foreach my $tab(@tabs){
 $hash{$tab}{'spane'}= $hash{$tab}{'frame'}->Scrolled('Pane',-bg=>'whi
+te')
             ->pack(-expand=>1,-fill=>'both');

 #now pack 2 side by side frames in the scrolled Pane
  $hash{$tab}{'f1'}= $hash{$tab}{'spane'}->Frame(-bg=>'hotpink', -padx
+=>15)
       ->pack(-side=>'left',-expand=>1,-fill=>'both',-padx=>15);

 $hash{$tab}{'f2'}= $hash{$tab}{'spane'}->Frame(-bg=>'lightseagreen',-
+padx=>15)
       ->pack(-side=>'right',-expand=>1,-fill=>'both');
}

#now make columns
foreach my $tab(@tabs){
  foreach my $fr('f1','f2'){
    #make  frames for each pair
     $hash{$tab}{$fr}{'subframel'} = $hash{$tab}{$fr}->Frame()
           ->pack(-side=>'left',-expand=>1,-fill=>'both');
     $hash{$tab}{$fr}{'subframer'} = $hash{$tab}{$fr}->Frame()
           ->pack(-side=>'right',-expand=>1,-fill=>'both');
  }    
}

#now fill columns

foreach my $val qw(IN_DIR IN_LIST OUT_TYPE BYTESWAP OUTPUTAUX ){
  foreach my $tab(@tabs){    
     foreach my $fr('f1','f2'){
 
     $hash{$tab}{$fr}{'subframel'}{'labentry'} =  
     $hash{$tab}{$fr}{'subframel'}->LabEntry(-label => "$val=");
     
     $hash{$tab}{$fr}{'subframel'}{$val}{'val'} = "$val-$tab-$fr"; 
     $hash{$tab}{$fr}{'subframel'}{'labentry'}->Subwidget('entry')->
          configure(-background=>'yellow',
          -width => 25,
          -textvariable => \$hash{$tab}{$fr}{'subframel'}{$val}{'val'}
+);
     
     $hash{$tab}{$fr}{'subframel'}{'labentry'}->configure(
              -labelPack=>[-side=>'left',-anchor=>'w'],
              -width => 20,
              );
     $hash{$tab}{$fr}{'subframel'}{'labentry'}->pack(-anchor=>'e');   
+ 
   
   }
 }
}

MainLoop;

__END__
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