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another problem is that I need GENE to always be first (not regular lexicographic sort)
That's doable...here's a sample (the sed and awk can easily be replaced by perl...left as an exercise):
#!/bin/ksh awk 'BEGIN { SORTCD["GENE"] = 1 SORTCD["CDS"] = 2 SORTCD["RNA"] = 3 } { print SORTCD[$3], $0 }' <<EOT | 1 1 RNA 1 1 GENE 1 2 CDS EOT sort -n -k2,3 -k1,1 | sed -e 's/^[0-9]* //'

In reply to Re^3: sorting a file - multilevel by runrig
in thread sorting a file - multilevel by ini2005

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