I would think that a UNIVERSAL::AUTOLOAD method would be the only way to catch this, if you want to avoid any predefinitions...

Another approach maybe to find all Wx:: classes and subclass them at startup... This may subclass a whole bunch of classes that you won't be using, but it avoids AUTOLOAD nastiness... Something like the following maybe:

use Wx;
my $symbol_table = Symbol::Table->New(PACKAGE=>'main::Wx');
while(my $package = each %$symbol_table) {
  eval "package Groninger::Wx::$package; use base 'Wx::$package;";
}
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This code doesn't recurse (so only packages directly in the Wx:: namespace will be subclassed) and it only works if the packages in that namespace have already been use'd. But that could be done automatically I suppose...

But perhaps it would then make more sense to generate them specifically for the packages you want to subclass using a syntax like:

use Class::SubclassSet Groninger => qw(Wx::App Wx::Frame Wx::Menu);
package Class::SubclassSet;
sub import {
   my ($this,$into,@classes);
   for my $class (@classes) {
      eval "package ${into}::$class; use base '$class';";
   }
}
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That would reduce the duplicate code you'd be typing, prevent redundant subclassing and avoid UNIVERSAL::AUTOLOAD;

(All code untested; just brainstorming here...)

Regards, Giel