It's hard to see why you would choose to use any language that you found an effort. I use Perl because it makes the tasks that I use it for easier than otherwise. I use Tk when I need a light weight user interface for something that I am using Perl for.

Perl has tremendous advantages for solving many sorts of small tasks very quickly. In general Perl is not best suited to large flagship applications that require native look and feel GUIs.

You haven't provided near enough information for us to actually help you make a decision, but by now I think we have provided you with a huge amount of information to provide guidelines for that decision.