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I don't know enough about the sorts of requests that might be made against your database, but
1. if using MySQL 4+, have you turned on the query caching? and 2. can you pre-populate or generate any reports off-line? i.e. if you know the reports that most users ask for, can you pre-build them at 1-6 a.m. (or whatever), when it does not matter if each query takes three minutes. Even running the queries will build the query cache for number 1. Finding the top 20% of the reports used 80% of the time means you can pre-build those or prime the cache. It all depends on your data and how dynamic the queries are. In reply to Re^2: Does DBI handle table alias?
by zebedee
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