You need to run the following little test to catch any errors with negative x and y values before firing off any benchmarks:

# tgol.t - Simple blinker test of Conway Game of Life Organism class
use strict;
use warnings;
use Organism;
use Test::More;
my $nblinks = 5;
my $ntests = ( $nblinks + 1 ) * 3;
plan tests => $ntests;

sub test_one {
   my $org = shift;         # Organism handle
   my $desc = shift;        # Test description
   my $expected = shift;    # Array ref of (sorted) expected cells
   my $nexpected = @{$expected};
   my $ncells = $org->count();
   my @cells = $org->get_live_cells();
   cmp_ok( $ncells, '==', $nexpected, "$desc cell count ($ncells)" );
   cmp_ok( scalar(@cells), '==', $nexpected, "$desc cell array count" 
+);
   is_deeply( \@cells, $expected, "$desc cell array" );
}

# Blinker pattern
my @blinker1 = (
   [ -101, -100 ], [ -100, -100 ], [  -99, -100 ],
   [ -101,  100 ], [ -100,  100 ], [  -99,  100 ],
   [   -1,    0 ], [    0,    0 ], [    1,    0 ],
   [   99, -100 ], [  100, -100 ], [  101, -100 ],
   [   99,  100 ], [  100,  100 ], [  101,  100 ],
);
my @blinker2 = (
   [ -100,  -99 ], [ -100, -100 ], [ -100, -101 ],
   [ -100,   99 ], [ -100,  100 ], [ -100,  101 ],
   [    0,   -1 ], [    0,    0 ], [    0,    1 ],
   [  100,  -99 ], [  100, -100 ], [  100, -101 ],
   [  100,   99 ], [  100,  100 ], [  100,  101 ],
);
my @sblinker1 = sort { $a->[0] <=> $b->[0] || $a->[1] <=> $b->[1] } @b
+linker1;
my @sblinker2 = sort { $a->[0] <=> $b->[0] || $a->[1] <=> $b->[1] } @b
+linker2;

# Initialization
my $org = Organism->new();
$org->insert_cells(@blinker1);
test_one( $org, "initial", \@sblinker1 );

# Pattern should just blink back and forth
for my $i ( 1 .. $nblinks ) {
   $org->tick();
   test_one( $org, "blinker $i", $i % 2 ? \@sblinker2 : \@sblinker1 );
}
[download]

prove tgol.t
[download]

#   Failed test 'initial cell count (11)'
#   at tgol.t line 17.
#          got: 11
#     expected: 15

#   Failed test 'initial cell array count'
#   at tgol.t line 18.
#          got: 11
#     expected: 15

#   Failed test 'initial cell array'
#   at tgol.t line 19.
#     Structures begin differing at:
#          $got->[0][0] = '-281474976710655'
#     $expected->[0][0] = '-101'

#   Failed test 'blinker 1 cell count (10)'
#   at tgol.t line 17.
#          got: 10
#     expected: 15

#   Failed test 'blinker 1 cell array count'
#   at tgol.t line 18.
#          got: 10
#     expected: 15

#   Failed test 'blinker 1 cell array'
#   at tgol.t line 19.
#     Structures begin differing at:
#          $got->[0][0] = '-281474976710655'
#     $expected->[0][0] = '-100'

#   Failed test 'blinker 2 cell count (11)'
#   at tgol.t line 17.
#          got: 11
#     expected: 15

#   Failed test 'blinker 2 cell array count'
#   at tgol.t line 18.
#          got: 11
#     expected: 15

#   Failed test 'blinker 2 cell array'
#   at tgol.t line 19.
#     Structures begin differing at:
#          $got->[0][0] = '-281474976710655'
#     $expected->[0][0] = '-101'

#   Failed test 'blinker 3 cell count (9)'
#   at tgol.t line 17.
#          got: 9
#     expected: 15

#   Failed test 'blinker 3 cell array count'
#   at tgol.t line 18.
#          got: 9
#     expected: 15

#   Failed test 'blinker 3 cell array'
#   at tgol.t line 19.
#     Structures begin differing at:
#          $got->[0][1] = '99'
#     $expected->[0][1] = '-101'

#   Failed test 'blinker 4 cell count (9)'
#   at tgol.t line 17.
#          got: 9
#     expected: 15

#   Failed test 'blinker 4 cell array count'
#   at tgol.t line 18.
#          got: 9
#     expected: 15

#   Failed test 'blinker 4 cell array'
#   at tgol.t line 19.
#     Structures begin differing at:
#          $got->[0][1] = '100'
#     $expected->[0][1] = '-100'

#   Failed test 'blinker 5 cell count (8)'
#   at tgol.t line 17.
#          got: 8
#     expected: 15

#   Failed test 'blinker 5 cell array count'
#   at tgol.t line 18.
#          got: 8
#     expected: 15

#   Failed test 'blinker 5 cell array'
#   at tgol.t line 19.
#     Structures begin differing at:
#          $got->[0][1] = '99'
#     $expected->[0][1] = '-101'
# Looks like you failed 18 tests of 18.
[download]

I left this tgol.t test program out of the root node because it was already way too long ... then forgot about it. Sorry 'bout that. Update: I've now remedied my oversight by adding the tgol.t test program above to the root node.