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I think you are convoluting the problem and your system even more. I would go the opposite direction and blank out both env vars you set.

If you have not installed 5.30 as root just erase it from your home dir including all additional packages it installed and make sure about that. Then use perlbrew to re-install perl 5.30. Then ask perlbrew to use 5.30 as the default perl for your account. Then install additional packages. Perhaps starting with cpanm. And report back if there is a problem. perlbrew will make sure that one perl's libraries and packages do not pollute another's.

If you have installed 5.30 as root, your problems are only surfacing now... I hope you are able to remove it and all its packages and restore the system perl and its packages.

If you want to investigate further before a re-install then use strace as Fletch suggested to see which libraries are causing the bad handshake.

you did neither of these

btw, it seems you posted already this to stackoverflow with very poor answers. None-the-less perhaps you could edit this post to notify us of it.

In reply to Re^3: XS.c: loadable library and perl binaries are mismatched (got handshake key 0xc100000, needed 0xc180000) by bliako
in thread XS.c: loadable library and perl binaries are mismatched (got handshake key 0xc100000, needed 0xc180000) by rgren925

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