Start by using a well tested and existing framework such as Catalyst
and you will have eliminated already a lot of common low-level vulnerabilities.
A program should be light and agile, its subroutines connected like a string of pearls. The spirit and intent of the program should be retained throughout. There should be neither too little or too much, neither needless loops nor useless variables, neither lack of structure nor overwhelming rigidity." - The Tao of Programming, 4.1 - Geoffrey James
My blog: Imperial Deltronics