An easier solution would be to, once the user is done editing all the textboxes, he should just close the window, or exit it, and the changes will be commited to the database. To do that, you have to place an "onload=script.cgi" on the BODY tag of your HTML, "script.cgi" being the one that actually writes this data to the DB.

I suggest you place a javascript confirmation alert before you actually write the data, just in case...