For efficiency you want something like this:
my $dir = '/Path/to/a/data/directory';
opendir my $DH, $dir or die "Cannot open '$dir' $!";
my %hash;
while ( my $file = readdir $DH ) {
next if $file =~ /~$/;
open my $FH, '<', "$dir/$file" or die "Cannot open '$dir/$file' $!
+";
while ( my $line = <$FH> ) {
next if /^#/ || !/\S/;
my ( $key, @values ) = split /\t/;
$hash{ $file }{ $key } = \@values;
}
}
Update: I realised that the while loop is incorrect, it should be:
while ( my $line = <$FH> ) {
next if $line =~ /^#/ || $line !~ /\S/;
my ( $key, @values ) = split /\t/, $line;
$hash{ $file }{ $key } = \@values;
}