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in reply to cleaving a sequence with specific alphabets

If I understood your question clearly, here is my solution. You can use negative look behind regex and split function to accomplsh it. TIMTOWTDI.

$string = 'APADPKGSTIDRPDAARTLTVHKCEQTDTRGVKEGTRNEDPQAECKPVSDVEFTITKLN +VD'; @arr = split /(?<!P)(K|R)/, $string; print @arr; output: ------- APADPKGSTIDRPDAARTLTVHKCEQTDTRGVKEGTRNEDPQAECKPVSDVEFTITKLNVD

Take a look at perlre and split function.

Prasad