Great question. When Andy Lester was in Toronto a few months back, he demoed Module::Starter for me at the pub afterwards, and it was very slick. I haven't used it yet, because I'm still at the point of learning and using Test Driven Development, progressing from Test::More to using prove with Test::Harness. (There's the additional challenge of fiddling with subversion for version control -- requires effort, but definitely worth it.)

I'll continue to learn all of that good stuff, once I've got it well under control, I'll move to Module::Starter, and the stuff that I understand by then will be taken care of for me.