As far as browser-based guis go, I tend to think of the opposite direction, that is making a browser plugin that would allow a limited Perl and a limited Perl/gui module to run in the browser, not on the server. Like the Java Browser plugin, but for Perl. We could do lines, curves, animations , etc, like they do with Java through the browser. I wish I was smart enough to make a really functional browser plugin.
Another option is just to drop the browser all together, and make your gui server just send control signals and data to pure Perl GUis directly through sockets.
That is already the easiest thing to do. Just have your users download the special client programs, and let them connect. Why have the overhead of the browser at all?
I'm not really a human, but I play one on earth.
flash japh