wxPerl which I and other monks are using, search for tutorials here and on perl.com.

Frozen Bubble (a game using SDL-Perl)

Digistrips (darn I wish they opened their code..) based on perl and TkZinc. This prototype for an air traffic control system apparently lets you drag simulated paper strips around a touch screen, TkZinc provides rich eye candy interface, etc. Anybody know about wxWidget code that could do things like this? Maybe I didn't do TkZinc because it didn't work on XP at the time. Apparently it does now. But development of the project seemed to be (and maybe still is) much slower than wxPerl.

If anyone else has collected useful perl GUI code/sites please let me know. For now wxWidgets seems to have the most "undiscovered promise"..

That said I'd guess the worst thing to do with perl is build a pacemaker, yup count me out. But I'm definitely not sure about how slow an OpenGL game would be using perl, after all once you've drawn something it is in the GL buffer right? Need a nice machine/graphics card to worry about that. I'm thinking maybe planetarium-style software might be difficult.. would like to be proven wrong though.

But I am working on some online "packaged software" and with a free software installer, and packaging with pp it doesn't look impossible anyway. Definitely a lack of tutorials/tools to make it easy though. I think it's a matter of try it and see if it works.