Personnally i'm using Qt designer for the design of the GUI. My view is that a GUI builders help you to increase your productivity. I don't see where is the interest of searching one hour during the good position of your widget, it's not the interesting thing. I prefer to loose time to read documentation to learn how to do something more interesting. Moreover i'm not sure that is possible to create a GUI without having to know to write one manually at all :-) Finally, i think that once you know how to make a GUI it's not really producive to repeat X times same things just for ethical reasons.