You will be doing it via Win32 API. Although it may seem rather unrelated at first have a look at Win32-Screenshot which provides a whole lot of window handling methods like: WindowFromPoint GetForegroundWindow GetDesktopWindow GetActiveWindow GetWindow FindWindow ShowWindow GetCursorPos SetCursorPos GetClientRect GetWindowRect BringWindowToTop GetWindowText IsVisible GetTopWindow Minimize Restore ScrollWindow. The XS part just calls the native Win32 API calls. As you can see the Perl wrapper code is very simple.