^ in a regex pattern means 'starts with'. No line starts with Lesle.
/43500$/ is incomplete. You have to say match it with $inp.
Try this:
#!/usr/bin/perl
use strict;
use warnings;
while(my $inp = <DATA>){
if ($inp =~ /Lesle/ .. $inp =~ /43500$/){
print "$inp\n";
}
}
__DATA__
41 Tommy Savage:408–724–0140: 12 2 2 Oxbow Court, Sunnyvale, CA 94087
+: 5/19/66: 34200
42 Lesle Kerstin: 408–456–123 4: 4 Harvard Square, Boston, MA 02133:
+4/22/62: 52600
43 JonDeLoach: 408–253–3 122: 12 3 Park St. , San Jose, CA 94086: 7/2
+5/53: 85100
44 Ephram Hardy:293–259–5395: 2 3 5 Carlton Lane, Joliet, IL 73858: 8
+/12/20: 56700
45 etty Boop: 245–836–83 57: 63 5 Cutesy Lane, Hollywood, CA 91464: 6
+/23/23: 14500
46 Wilhelm Kopf:846–836–2837 : 693 7 Ware Road, Milton, PA 93756: 9/2
+1/46: 43500
47 Norma Corder:397–857 –2735: 74 Pine Street, Dearborn, MI 23874: 3/
+28/45: 245700
48 James Ikeda: 834–938–8376: 2 3 445 Aster Ave. , Allentown, NJ 8374
+5: 12/1/38: 45000
49 Lori Gortz: 327–832–5728: 3 465 Mirlo Street, Peabody, MA 34756: 1
+0/2/65: 35200
50 Barbara Kerz:385–573 –8326: 83 2 Ponce Drive, Gary, IN 83756: 12/1
+5/46: 268500
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