This reference to Semiperfect Numbers says that every multiple of a semiperfect number is semiperfect, which makes me think some form of sieving process would eliminate many cases quickly.

Update: I found a paper using google: Sums of Divisors and Egyptian Fractions which has some interesting results on weird numbers. Two things it mentioned are that a computer search proved there are no odd wierds below 2^32, and that all abundant numbers of the form 3^a * 5^b * 7^c are semiperfect (where a, b, c > 0).