While I haven't any experience with Win32::GUI, I've used Perl/Tk successfully for this exact problem. The key methods are getOpenFile and getSaveFile Here's a short example:

#!/usr/bin/perl -w

use Tk 8.0;
use strict; 

my $mw = MainWindow->new( -title => 'File Test' );
my $menu_bar = $mw->Menu;
$mw->configure( -menu => $menu_bar );

my $file_mb = $menu_bar->cascade( -label => '~File', -tearoff => 0 );

$file_mb->command( -label => 'Open', -underline => 0, -command => \&f_
+open );
$file_mb->command( -label => 'Save', -underline => 0, -command => \&f_
+save );
$file_mb->separator;
$file_mb->command( -label => 'Exit', -underline => 1, -command => sub{
+exit} );

MainLoop;

sub f_open {
  my $filename = $mw->getOpenFile( -title => 'Open File:',
    -defaultextension => '.txt', -initialdir => '.' );
  ### do something with $filename
  warn "Opened $filename\n";
}

sub f_save {
  my $filename = $mw->getSaveFile( -title => 'Save File:',
    -defaultextension => '.txt', -initialdir => '.' );
  ### do something with $filename
  warn "Saved $filename\n";
}

#
[download]

Note that Question 16.2. - Is there a file selector? of the (somewhat stale) Perl/Tk FAQ lists several alternatives. Which, if any, of these is what got built into the Tk of ActiveState Perl, I don't know...

In the ActivePerl FAQ: Is there a way to do GUI programming with ActivePerl?

It refers to Win32::GUI, which seems to be the module's author's page; it also has a lot of useful info about other Win32 modules, as well as links to precompiled versions for the compiler impaired.

Below is some (untested) code based on a message from the Win32::GUI mailing list:

use Cwd;

# returns selected file name; undef if Cancel
sub file_open_dialog {
  my $file_spec = "*.bmp\0" . " " x 256; # init a C-friendly buffer
  my $dir = cwd;

  GUI::GetOpenFileName(
    -title => 'Load/Save File',
    -owner => $Win,
    -directory => $dir,
    -file => $file_spec,
  )
}
[download]

Win32::GUI Installation Tip:

If you don't have a C compiler to build the Win32::GUI module and you have ActivePerl, do:

  
PPM install --location http://Jenda.Krynicky.cz/perl/ Win32-GUI
[download]

Originally posted as a Categorized Answer.

The Tk in ActiveState Perl includes a Tk::FileSelect module which provides a generic file selection dialog.

A question: I can`t seem to open a filehandle in the functions for writing to a file?

Opening for reading is OK, writing fails.

A question:...

Sorry, but that is not an answer

Also, your question is indecipherable, see How do I post a question effectively?