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Re^2: Reduce RAM requiredby onlyIDleft (Scribe) |
on Jan 09, 2019 at 16:27 UTC ( [id://1228263]=note: print w/replies, xml ) | Need Help?? |
1. ATGC frequencies are never equal except by fluke 2. DNA sequences have periodicities or features at different size ranges 3. Sequence read in forward and reverse orientations almost always yield different biological meanings But about how reversing alternatively, changing shuffle window size etc will change signal / noise ratio would be a multi-week study by itself So your advice on keeping it simple and easy in terms of the coding is well taken :) Thank you!
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