Are you able to provide any more detail. It looks like ActiveTcl is a Microsoft Windows module so not sure how this relates to MacOS.
As you are binding to C library calls as suggested with your Tcl reference, there are likely a lot of dependencies that could cause this kind of problem.
It would be great if you could expand on your environment a little to guide the investigation.
ED: As OP have advised ActivePerl is indeed available for Mac OSX - did not know that - thanks. I wonder if the Tk modules require a local running X Server like XQuartz perhaps? Not quite so game to install ActivePerl to find out but would def. be interested to know if others are using it with Tk.
I assume you have installed ActiveTCL (https://www.activestate.com/activetcl/downloads ) and aren't just trying to use the Perl Module - the error smells to me like a missing library dependency.