Centos 7 uses perl 5.16 as standard. Some perl code might need a bit more recent perl and for this you have the opt-perl-522* packages. They are available from the packages.endpoint.com repository.

So you can either install perl 5.22 via these packages or (and this is what I would do) just install MIME::Base64::URLSafe from source, ideally into a non-system tree. The module is very old and therefore does not require perl 5.22 or anything like it. Should run fine on 5.8.8 and probably even earlier.

And are there ways to avoid this MIME::Base64::URLSafe.

Sure, just don't use it.