##
43:1:1-5; 27:3:7-9; 65:1:4; 65:1:18
##
##
$seq =~ s/
(\d+):(\d+):(\d+)
(?:;|\s)*
(\1):(\2):(?{1+($3|$6)})
/$1:$2:$3-$6/xg;
##
##
#OUTPUT
43:1:1-2; 43:1:3-4; 43:1:5-6; 27:3:7-8; 27:3:9; 65:1:4-18