G'day bliako,
I went through this process about 18 months ago.
I asked similar questions to you and, like you, I got a lot of replies.
It ended up a rather long thread; read it all if you want; here's my three main posts:
Here's a brief, non-exhaustive, overview of features:
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The Win10+Cygwin provides a Unix environment.
It's not substantially different from the Linux (OpenSUSE) machine I use for $work.
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I run bash on a mintty xterm (Cygwin64 Console).
It provides a vi interface on the command line (set -o vi in ~/.bashrc).
It has all the usual Unix commands and utilities.
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I have Perlbrew installed. I initially used this to install Perl 5.30.0;
I subsequently used the same to upgrade to 5.32.0 and later to 5.33.5.
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I run an X Server with Cygwin XLaunch.
Perl Tk programs work fine with this.
(There's actually 16 X Servers available.)
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I access many open source applications via aliases:
soffice file.docx (LibreOffice); foxit file.pdf (Foxit); and so on.
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I have an Apache webserver set up.
Other webservers that are started by Perl web frameworks, e.g. Dancer2, also work without any problems.
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I run network-related utilities, such as ssh and git, almost every day.
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... and so on ...
In the main, I've had no trouble installing Perl modules.
One issue I had, took me a while to sort out: "cpan: Terminal does not support AddHistory.".
With another, I needed help from fellow monks: "Update XML::LibXML - can't find "xlocale.h"".
There's a number of open source applications that I access directly from Win10: Firefox; Thunderbird; Vlc; and others.
I use this setup five days a week for $work; and seven days a week for my own projects.
Overall, I'm very happy with what I have.
I felt this was getting overly long; I could've written a lot more.
Please ask if you have any specific questions about things I haven't touched on, or areas where you'd like further details.
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"And you do introduce another iceberg: Tk and X-server."
I'm not sure what you mean.
A daunting heap of problems in front of you; and an even greater mass, hidden from sight, waiting to sink your ship? :-)
I write a lot of Tk programs: many posted here; many more for personal use.
I don't have any problems with the setup I described above.
I do have this file, in my home directory, which might help with some of your problems.
# .bash_vars
# To be sourced by .bash_profile.
# Use for potentially volatile environment variables.
# Saves having to make repeated edits to .bash_profile.
# Also, can be sourced independently.
set -a
# For X11
DISPLAY=:0
LIBGL_ALWAYS_INDIRECT=1
# ... irrelevant personal variables ...
# For Tk
XFT=1
# For Git
SSH_ASKPASS=
set +a
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