If certain things are expected to match more than 32766 times, you need to break it down.

So if the following exceeds the limit,

a+
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you have to use

(?:a{1,32766})+
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So,

/\G (?: \s++ | \# .*+ )++ /xgc
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becomes

/\G (?: (?: \s++ | \# .*+ ){1,32766}+ )+ /xgc
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Or maybe even

/\G
   (?: (?:
        (?: \s{1,32766}+ )++
      | \# (?: .{1,32766}+ )*+

   ){1,32766}+ )+
/xgc
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