Inspired by the C-Reduce project, which reduces C programs that cause compiler crashes to a minimal program that still causes the crash, I have started perl-reduce, which does the same for perl programs which segfault, cause valgrind issues, etc. The first draft is at:

https://github.com/blekko/perl-reduce

and I'm hoping to collect some user experiences for a bit more tweaking before widely advertising it in the perl community. If you have a crasher that you've never narrowed down because it looked too tedious, please give perl-reduce a try.