YAWTDI

$line =~ s/[(),;]//g;
my @split1 = split " ", $line;
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And yes, once you have these split up, they can be used in numeric calculations.

Just a quick note, when you're referring to a single element of an array, use $split1[0] rather than @split1[0]. See "perldoc -q @" and look at the answer for "What is the difference between $array[1] and @array[1]?"