One big adjustment for me at the current job is the heavy use of spreadsheets. Once you see a non-programmer type whip up some formulas and slice and dice you see why. The great upside of this for me is that Perl has great Excel support. I've integrated spreadsheet read/write/filtering into a Perl-based toolset we use using Spreadsheet::ParseExcel and Spreadsheet::WriteExcel and the results have been great.