http://qs321.pair.com?node_id=171329

Many of us deal with MySQL databases that are accessed exclusively via Perl. If performance isn't up to expectations, Perl can get blamed. To make matters worse, some of us get little or no DBA support when dealing with MySQL performance. ("You're not using Oracle|SQL Server? You're on your own.")

With that in mind, here is a no-direct-Perl-content recommendation for two Linux Magazine articles on MySQL performance (found via blakem's post about an upcoming Silicon Valley Perl Mongers talk):

There's stuff in here that can save you hours of pouring over the docs.

The author also has a presentation on Building Maintainable and Fault-Tolerant MySQL Applications with Perl.