#!/usr/bin/perl
use strict;
use warnings;
use feature 'say';
use Mojo::DOM;

my $html = '<ul><div class="txt" style="position:absolute; left:84px; top:73px;"><span id="f1" style="font-size:11px;vertical-align:baseline;color:rgba(0,0,0,1);">technology of S2S translation, also known as Spoken Language Translation (SLT),</span></div><div class="txt" style="position:absolute; left:44px; top:73px;"><span id="f1" style="font-size:11px;vertical-align:baseline;color:rgba(0,0,0,1);">is a new application of AI,</span></div><li>there</li><li>everyone</li></ul>';

my $dom = Mojo::DOM->new( $html );

$dom->find('span')->each( sub { $_->content( $_->content =~ s/Spoken/Derp/r ) } );
say $dom->content;